The Experimental Plant Systems Biology Lab at KU Leuven

Engineering plant chronobiology for climate adaptation

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We study and engineer the plant circadian clock, a molecular oscillator that allows plants to tell the time and adapt to seasonal environmental changes.

The genetic architecture of the plant circadian clock. The clock is comprised of interconnected transcription factors that control gene expression at different times of the day. DNA-binding transcription factors are shown in black. (Adapted from Mehta et al., 2021)

Accurately telling the time and predicting when the next day will begin is a matter of life and death for plants. As living beings that photosynthesise in the day and respire at night, most plants need to partition their most important metabolic functions temporally. In fact, an estimated 30% of gene expression in plants is controlled by their internal circadian clock.

Our lab aims to develop a sophisticated understanding of how the plant circadian clock controls all aspects of plant growth at the molecular level. We are also interested in how plants utilise the clock and other processes to help adapt to new geographic environments, something of paramount importance in a world experiencing accelerating climate change.